Texas has thrived as an underdog this year and should be able to pull off another upset, this time over Oklahoma State. Meanwhile, Ohio State is a 33-point favorite but should still be able to cover against Illinois while Louisville should look out for Houston, a 16-point underdog against the Cardinals, this week.
Baylor and Texas remain atop this week's Big 12 Power Rankings while Kansas State cracks the Top 5 as the Wildcats are riding a three-game win streak and Texas Tech, who has lost three in a row, continues to struggle.
Starting wide receivers Mike Davis and Jaxon Shipley each scored for the Longhorns in their win over West Virginia last week while Adrian Phillips came on strong against the Mountaineers as well. But Johnathan Gray and Chris Whaley, who sustained season-ending injuries in the victory, will be sorely missed.
Chris Whaley's absence leaves huge shoes to fill for Desmond Jackson, but, with 11 starts already under his belt, the junior they call "Tank" should be more than able to take advantage of the opportunity.
Georgia has had a mostly disappointing season so far but has a chance to knock off a suprisingly solid Auburn squad at home this week while Baylor faces another tough test hosting Texas Tech on Saturday and Duke continues its improbable run by visiting Miami this weekend.
Marcus Mariota's poor performance in Oregon's loss to Stanford last Thursday means Florida State freshman phenom Jameis Winston is now the favorite to win the Heisman. But Bryce Petty's Bears are also undefeated and Johnny Manziel is on pace to have an even better year than the one he had when he won the Heisman last season.
Losing Chris Whaley for the rest of the year means Texas loses the heart and soul of its defense, as well as one of the most talented and productive members of its defense. Desmond Jackson has plenty of starting experience and was outstanding against West Virginia but there's no replacing Whaley.
Converting red zone opportunities into touchdowns was a problem in the first half against West Virginia but the Longhorns were able to make up for it in the second half and overtime. They may be able to make up for such mistakes against a team like Oklahoma State.
He started out as the third-string quarterback at Oklahoma State and has moved up and down the Cowboys' depth chart but, with a few more wins under his belt this year, Clint Chelf seems to have cemented himself as the Pokes' man behind center.